Senior Scientist, Mass Spectrometry, Early Oncology

Senior Scientist, Mass Spectrometry, Early Oncology

Join our Boston R&D chemistry team as a Senior Scientist, where you'll use your expertise in small-molecule mass spectrometry to analyze a wide range of drug-like small molecules, linkers, payloads, and new modalities using UHPLC-MS techniques. As an integral member of our Analytical, Structural, and Chromatography (ASC) team, you'll work on method development, maintain instruments at peak performance, and bring in relevant new analyses to support chemistry projects. This is a hands-on laboratory position and requires you to work onsite. We are dedicated to building strong research teams that embrace the diversity of talents of team members and allow the larger group to grow and learn together to accomplish our collective goal to improve human health.

Accountabilities:

As a Senior Scientist, you will be part of our high performing lab-based team in Oncology R&D. You will perform hands-on experimentation to analyze and quantify compounds within challenging timelines. You will collaborate across disciplines and develop bespoke methods as needed to help drive portfolio delivery. Your understanding of mass spectrometry within a drug discovery environment will be augmented via collaborative knowledge sharing and in-house training. You will also assist with the site transition to Kendall Square, including planning and installations.

Essential Skills/Experience:

- Bachelor's or Master's degree in analytical chemistry or related field with 8+ years of industry experience, or Ph.D. in analytical chemistry with 3+ years of industry experience, in roles that focused on use of mass spectrometry analysis and data interpretation skills.

- Solid knowledge of mass spectrometry and reverse-phase chromatographic techniques, including method development and instrument troubleshooting.

- Detailed understanding of the use of analytical techniques and data interpretation to solve complex scientific questions.

- Demonstrated lab-based experience running LC-MS single-quad, triple quad, and high-resolution instrumentation for analysis of small molecule compounds.

- Strict adherence to laboratory safety and operating procedures in handling all new chemical entities, and particularly OEB 5 and OEB 6 compounds.

- Excellent written and oral communication skills. The ability to communicate complex information clearly.

- First-rate time management skills, forward planning, and focus on delivery.

- Steady performance, demonstrating values and behaviors, and strong interpersonal skills are a must.

Desirable Skills/Experience:

- Hardware experience with Waters and Agilent

- Software experience with MassLynx, MassHunter, and Chemstation.

- Knowledge of pharmaceutical drug discovery

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. We balance the expectation of office responsibilities while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca?

As Clinical Development Physicians and Scientists in Oncology, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. Our pipeline is a testament to our growth, both now and in the future.

Are you ready to make a difference? Apply today and join us in our mission to eliminate cancer as a cause of death!

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.