Senior Scientist in Process Analytical Technology (PAT)

SeniorScientistinProcess Analytical Technology(PAT)- Make a Meaningful Impact on People's Lives!

Are you ready to take your career to the next level and make a meaningful impact on people's lives with life-changing medicines? Join our Operations team inMacclesfieldas aSeniorScientist and be part of a team whereeveryone feels a personal connection to the people weimpact.

At AstraZeneca, our Operations team has a big ambition: to deliver more medicines to patients, quicker and more affordably. We are driven by our commitment to deliver accelerated growth for AstraZeneca and to make people's lives better. 

In Pharmaceutical Technology and Development (PT&D),within Operations,we are the bridge between brilliant science and innovative medicines that help millions of people. We work across the entire value chain, designing and delivering active ingredients, formulations and devicesrequiredto support new medicines – from supplies for use in early toxicology studies and clinical trials to developing the technology to ensure drugs can be scaled up for commercial manufacture.

AtGlobalProduct Development (GPD) inGothenburg, a sub-division of PT&D, we focus on the fields of Oral Controlled Release Drug products and Immediate Release Drug Products. You will join a vibrant team that is working on the next generation of medicines and play a key role in the development of new medicinal products.

We are currentlylooking for a Senior Scientist for PAT in our Product and Process Controlgroupto strengthen our capabilities inthedevelopment and implementation of enhanced control strategiesusing the newest technologiesto our late phaseportfolio.If you have a solid scientific foundation in this domain and the aspiration to grow into an expert, this role offers an excellent fit.

Whatyou’lldo

As a Senior Scientist, you will design, develop, and deliver high‑quality enhanced control methods by applyingexpertisein Process Analytical Technology (PAT), chemometrics, and advanced processmonitoringand control. Hands‑on laboratory work will be a core part of your role.

You will collaborate with cross‑functional project teams, contribute to regulatory documentation, and support digital initiatives that implement innovative monitoring and control tools across continuous manufacturing platforms.

You willparticipateinthe development,validation and technical transfer of methods and PAT tools to enable robust product control strategies across Operations. You will also champion a future‑focused, innovative mindset, advancing data science, predictivemodellingand simulation, and artificial intelligence to drive digitally oriented approaches.

Essential for the role:

-BSc,MScor equivalent in a relevant discipline(chemistry, pharmacy, engineeringetc.)with experience in the use of PAT in the Pharmaceutical or Chemical industries and/or postgraduate experience in Academia with a PAT industrial focus.

-A strong understanding of keyPAT(e.g.,NIR,Ramanand microwavespectroscopy)

-PAT method developmentexperience,implementationand use ofmulti-variatedata analysis/ Chemometrics (MVDA, PCA, PLS)in common software platforms (SIMCA, Python,MATLAB,PLS Toolbox etc.)

- Ability to document and present your work concisely and comprehensibly

- Strong collaboration, communication, and leadership skills

-An understanding of the principles and management of Safety, Health & Environment (SHE)

Desirable for the role:

-Demonstratedexperience of ensuring compliance with operational requirements (GMP, GAMP, Process Safety, Data integrity, Change Control)

-Experience ofdeveloping control strategies for pharmaceutical commercial manufacturing processes

- Basic scripting skills (e.g. Python,Matlab, R)

- Experience with digital tools supporting enhanced control strategies (DCS, PAT management system, APC,Multivariate monitoring platform)

-Knowledge of pharmaceutical process equipment/technology for continuous processes

Why AstraZeneca?

We offer an inclusive environment where you can grow your career while making a positive impact on people's lives. Our team is a multigenerational workforce that thrives on curiosity and problem-solving. We are committed to sustainability and leading the way in delivering Lean processes that drive greater efficiency and speed.

Are you ready to step up and lead in a fast-paced environment that rewards commitment and offers diverse career opportunities? Join us at AstraZeneca and be part of our journey towards making people's lives better!

So,what’snext?

Don'tmiss this opportunity to make a meaningful impact on people's lives – apply now!