National Sales Director, US BioPharma, Respiratory and Immunology

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big, and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring new ideas to life.

The AstraZeneca’s US BioPharma Respiratory and Immunology (R&I) Team holds a unique position in respiratory disease, including asthma, chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF), with a range of differentiated potential medicines in development by using novel combinations, biologics and devices. The pipeline also has several promising assets in inflammatory and autoimmune diseases within areas such as psoriasis, psoriatic arthritis, gout, systemic lupus and rheumatoid arthritis.

The National Sales Director (NSD) of the US BioPharma R&I Sales and Marketing Team will play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives. The NSD will be based in Wilmington office and will report directly to the Executive Director of Sales and Marketing, and lead a team of Commercial Business Directors (CBDs) and a 200+ sales team, with a view to expand further as the Franchise grows.

The NSD will be accountable for collaborating with the Franchise Head and Core Value Team (CVT) to shape the go to market strategy for future launches and indications. They will also be responsible for delivering the R&I sales targets across the country while leading and developing their teams.  The successful candidate will be a strong people leader with a proven track record of broad commercial experience. They will have a successful track record of establishing a high performance, high reward culture while attracting, developing, and retaining talent. Additionally, this leader will be experienced in leading and motivating large scale, diverse and inclusive sales teams in order to optimize team performance and create an environment of inclusion and belonging. The NSD will communicate a compelling sales strategy and vision and lead with drive and energy by taking appropriate risks and motivating individuals and teams to perform at the highest level.  Additionally, this role is expected to partner across an Alliance of two companies with a shared vision and goal, delivering across all customer segments and collaborating with key Commercial stakeholders (Marketing, Market Access, IBEX, HR and Finance)to develop and successfully execute National and Geographic strategies.    

Main Duties and Responsibilities

• Lead the strategic direction, design, execution and measurement of go to market strategies, tactics and activities to deliver on the sales goals and targets
• Understands and anticipates market trends, customer mix, local influences, Rx trends and competition when designing high-impact business plans tailored to meet customer needs for each geography
• Role models the AZ Values and Behaviors:  employs enterprise thinking, entrepreneurial leadership, engenders trust, empowers others, has courageous conversations, creates inclusive & diverse teams and makes difficult decisions
• Responsible for leading and developing regional Commercial Business Directors and members of the sales team, including but not limited to sales incentives, performance development, talent management and career development, develop a diverse pipeline for future commercial leaders through mentoring, coaching, and continuous feedforward
• Ability to establish a clear commercial strategy, vision and purpose and communicate it with passion and authenticity to the organization
• Scientific mindset and robust knowledge of all AZ Core Growth Platforms and of our strategic TA’s/brands
• Exceptional strategic thinking, judgement and influencing skills to ensure strong commercial focus and consistency
• Ability to understand and appropriately challenge forecast assumptions. Regularly communicate performance updates/forecasts to senior leadership
• Ability to gain alignment on critical issues/initiatives and to inspire and influence cross-functional partners

• Lead through change with transparency and confidence, to ensure effective engagement of all stakeholders and teams

• Able to express complex ideas and strategies in clear, simplified and compelling ways to influence multiple and senior stakeholder groups
• Use robust analytical rigor to frame situations and incorporate new perspectives and ideas
• Embraces new ways of working / thinking to drive innovation including but not limited to digital, ecosystems, patient centricity, dynamic healthcare environment

Essential Requirements

• Bachelor's Degree required; preferably in business, marketing or the sciences
• 8+ yrs of demonstrated Commercial Leadership (non-Sales) and Second Line Sales Leadership experience with a combination of: pharmaceutical, healthcare, scientific, clinical, institutional or related industry experience.
• Proven track record of consistent achievement or overachievement delivering strategic and operational plans within a therapeutic or business area
• Ability, ambition and experience to grow career and lead cross functional commercial teams, with increased level of complexity, size and structure.
• Ability to be mobile within US and ex-US markets.
• Thorough understanding of customer segments and regional market dynamics; proven ability to link science to patient to commercial opportunities
• Strong financial acumen with the ability to assess and drive results
• Experience with P&L drivers; sales forecasts, operational budgets, expense management, contribution and top-line vs. bottom line budgets.
• Track record of strong cross-functional collaboration, influence and experience gaining stakeholder alignment to move key initiatives forward
• Proven track record and demonstrated experiences in evolving Customer Facing Model and of making relevant trade-offs to ensure organizational/ enterprise success
• Demonstrated commercial leadership of pre-launch and launch activities
• Successful experiences attracting and developing diverse talent/ teams and optimizing team performance in direct and matrixed leadership roles
• Strong change and agile leadership, both leading transformational change and leading through ambiguity
• Strong presentation and negotiation skills with senior leadership
• Ability to travel across the nation 60% of the time.

PreferredRequirements

• MBA
• Experience building launch teams
• Franchise leadership experience
• Working relationships with top External Scientific Experts (ESEs)

Next Steps – Apply Today!

Date Posted

13-Aug-2026

Closing Date

20-Aug-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.