Computational Biology Intern, PhD Students

We are looking for doctoral level students majoring in Computational Biology, Bioinformatics, Systems Biology, Biomedical Informatics (with a specialization in AI, ML, or genomics) or a related discipline for a 10-week internship role in Waltham, MA from June 1st to August 7th.

Position Duties:

• Design and Build the Agentic Framework: Lead the design, rapid prototyping, and testing of a multi-agent AI system using Python and modern LLM/agentic frameworks (e.g., LangChain, AutoGen, Google ADK or similar).

• Infuse and Validate Biological Domain Knowledge: Act as the "subject matter expert" to guide the AI. You will apply your deep knowledge of oncology/immunology to curate training data, design prompts for hypothesis generation, and critically evaluate the AI's outputs.

• Integrate and Demonstrate Pipelines: Integrate the separate agents into a single, end-to-end proof-of-concept pipeline constructing.

Position Requirements:

• Doctoral level students majoring in Computational Biology, Bioinformatics, Systems Biology, Biomedical Informatics (with a specialization in AI, ML, or genomics) or a related discipline. Candidates must have an expected graduation date after August 2026.

• High-Dimensional Genomics Data Handling: Proven experience in cleaning, preprocessing, and analyzing large biological datasets, such as RNA-seq, scRNA-seq, proteomics, or genomic data, is required.

• Coding Proficiency: Coding skills in R and Python, including libraries for scientific computing (NumPy, Pandas), are required.

• Agentic Frameworks & LLMs: Direct, hands-on experience with orchestration frameworks like LangChain, AutoGen, CrewAI, or similar tools used for building multi-agent systems and leveraging Large Language Models (LLMs) is required.

• Oncology/Immunology: Specific experience or coursework focused on molecular pathways, disease mechanisms, and the interpretation of gene expression data are a plus.

• Deep Learning/ML Expertise: Experience with deep learning frameworks like PyTorch or TensorFlow is a plus.

• Ability to report onsite to Waltham, MA 3-5 days per week. This role will not provide relocation assistance.

• US Work Authorization is required at time of application.

• This role will not be providing OPT support.

• Compensation: $48 hourly

Date Posted

17-Dec-2025

Closing Date

15-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.