Senior Market Access Manager

Do you have expertise in, and passion for Market Access and creating value for our customers and patients?  If so, AstraZeneca might be the one for you?

ABOUT ASTRAZENECA

AstraZeneca is a global, global, science-led, patient-focused Biopharmaceutical business that focuses on the discovery, development, and commercialization of prescription medicines for some of the world’s most serious diseases. But we are more than one of the world’s leading pharmaceutical companies. At AstraZeneca we are dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There is no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning, growth, and development. Our strategic priorities reflect how we are working to deliver our strategy and achieve our Purpose. As a workforce, we are the catalyst for our values: we are entrepreneurial; we do the right thing; we play to win; we put patients first and we follow the science. As a company we appreciate and take great pride in each team member where every person is brought together through shared values, that underpins a shared purpose. There is no better place to feel inspired and energised. Answer unmet medical needs by pioneering the next wave of science, focusing on outcomes and crafting the patient ecosystem.
At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. Join the fastest-growing pharmaceutical in our markets, set up to fuel further growth. Be part of our shared ambition and pride: our strong heritage, our turnaround story, and early investment and commitment in international markets. There’s no better place to feel inspired and energized.

ABOUT THE MARKET ACCESS TEAM

You will join a high‑performing Market Access team that thrives at the edge of what’s possible—diverse in backgrounds, united by purpose, and energized by solving hard problems in unconventional ways. On Monday, you might whiteboard a fresh payer narrative with a health economist and a clinician; by Wednesday, you’re pressure‑testing a contracting idea over coffee with a policy lead who challenges your assumptions; on Friday, you’re celebrating a milestone because a bold, data‑backed approach unlocked access faster for patients who can’t wait. We’re driven and accountable, curiosity in our debates in everything we do. If you’re solution‑oriented, resilient when the path isn’t obvious, and excited to think differently to co‑create with stakeholders, you’ll feel at home here and you’ll see your impact, quickly, in Rare Diseases and Oncology.

What You will do

You will be a critical player in the success of our Oncology and Rare Diseases portfolio by translating scientific leadership into real-world access for patients with life‑threatening, serious diseases. You will shape and execute strategic medical imperatives across the asset lifecycle—building the value story early, informing evidence generation, and ensuring launch and post‑launch excellence. Day to day, you will engage and co‑create with medical experts, diagnostic specialists, payers, and patient advocacy groups to identify barriers across the patient journey, promote earlier diagnosis, and design pragmatic solutions that improve quality of care and speed time‑to‑access. You will develop a deep scientific and medical understanding of the disease landscape (including diagnostics and treatment pathways), synthesize insights from clinics and systems, and convert them into compelling payer strategies, HTA narratives, and contracting options. You will partner closely with Medical, HEOR, Policy, and Commercial to generate and translate evidence—clinical, RWE, and economic—into clear, credible value communication and negotiation readiness. You will track and shape the external environment, anticipating policy shifts, budget dynamics, and stakeholder needs, while measuring impact through well‑defined KPIs and continuously optimizing our approach. Throughout, you will bring a solution‑oriented mindset and resilient execution, fostering mutually beneficial partnerships that unlock sustainable access for patients who need it most.

Job Description:

• Access Strategy: Lead end‑to‑end Funder and HTA strategy from early launch prep readiness and evidence shaping to launch and in‑line optimization; define clear access objectives and KPIs per therapeutic area.

• Evidence Planning: Partner with HEOR/Medical to identify evidence gaps and inform clinical, RWE and economic model needs aligned to payer questions.

• Value Proposition: Craft and continually refine value stories, core value dossiers, and objection handlers, amongst others

• Scenario Planning: Pricing Business Cases, Budget Impact against local policy and affordability dynamics.

Key Responsibilities:

• External Engagement and Internal Cross Functional Collaboration.

• Stakeholder Co‑Creation: Build trusted relationships with payers, HTA committees, policy makers, clinicians, diagnostic specialists, patient advocacy groups and co‑design pragmatic access pathways.

• Negotiations & Submissions: Lead or coordinate Dossier and/or HTA/payer submissions, price/access negotiations; ensure high‑quality, compliant, accurate materials and rapid turnaround on queries.

• Policy Shaping: Monitor and contribute to policy developments (reimbursement frameworks, formulary processes, health technology prioritization), providing credible input that advances patient access.

• Key Responsibilities – Pricing, Policy Shaping & Governance

• Pricing Strategy: Recommend list/net pricing, tender approaches, and affordability programs (PAP), aligned with global and local policies

• Compliance: Ensure adherence to AZ policies and governance; maintain robust documentation, audit readiness, and nominated signatory alignment for access materials where applicable.

• Key Responsibilities – Cross‑Functional Leadership

• Launch Excellence: Orchestrate market readiness, stakeholder mapping, negotiation playbooks, and post‑launch performance tracking; drive course corrections based on KPIs.

• Insight to Action: Systematically capture Funder and system insights and convert them into strategy updates, evidence requests, and field guidance.

• Team Enablement: Coach commercial field colleagues on Funder value messaging, economic model use, and objection handling; elevate access fluency across the organization.

• Responsibility to promptly collect and report any adverse events and product quality complaints received from any source. All such cases must be documented accurately and submitted to the designated department within one business day of becoming aware of the information, ensuring compliance with company policies and applicable regulatory requirements.

• Responsibility to complete Adverse Event training during initial onboarding and then annually thereafter.

If this sounds appealing, please read on to understand the experience and skills we’re looking for…

ESSENTIAL SKILLS AND EXPERIENCE REQUIRED

• Completed Bachelor’s Degree in Life Sciences, pharmacy, health economics, public health, or a business field

• Management and Healthcare Experience: Preferably, at least 5+ years in Commercial, Market Access/HEOR/ or Pricing & Reimbursement in Pharmaceutical Sector or consulting, with a strong record in Oncology and/or Rare Diseases.

• HTA & Payer Submissions: End‑to‑end experience leading HTA/payer submissions, including evidence alignment, dossier development, stakeholder Q&A, and panel preparation.

• Pricing: Proven capability in pricing strategy, budget impact modeling, and innovative agreements

• Health Economics & RWE: Working proficiency with cost‑effectiveness models, BIAs, sensitivity analyses, and translating RWE into payer‑relevant value.

• Stakeholder Engagement: Track record building trusted relationships with payers, policy makers, clinicians, diagnostic specialists, and patient organizations; skilled in co‑creation and negotiation.

• Policy & System Knowledge: Understanding of SA reimbursement pathways, and evolving policy landscape.

• Cross‑Functional Leadership: Ability to align Medical, HEOR, Commercial, Regulatory, Policy, and Finance; experience orchestrating launch excellence and post‑launch optimization.

• Communication & Influence: Exceptional ability to simplify complexity, craft compelling value stories, and influence senior stakeholders; strong written materials (dossiers, objection handlers, slide narratives).

• Analytical & Strategic Agility: Structured problem‑solver with data literacy and comfort with ambiguity; adept at scenario planning and translating insights into action.

• Governance & Compliance: Knowledge of promotional and access‑related compliance requirements, documentation standards, and audit readiness; alignment with AZ policies and local codes.

• People & Team Skills: Collaborative, solution‑oriented mindset with resilience; mentoring/coaching experience a plus.

• Digital / AI Fluency: openness to new digital platforms.

Why AstraZeneca?

We are proud to have achieved Top Employer certification in South Africa, Kenya, and Nigeria, for 2026. This distinction is a confirmation of our commitment and ability to sustain people, partnerships, and employee engagement and foster an innovative workplace environment.

At AstraZeneca, we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare. Join the fastest-growing pharmaceutical in our markets, set up to fuel further growth. Be part of our shared ambition and pride: our strong heritage, our turnaround story, and early investment and commitment in international markets. There’s no better place to feel inspired and energized.

SO, WHAT’S NEXT?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!

Click the link to apply no later than 12 May 2026 and we’ll be in touch as soon as we can.

WHERE CAN I FIND OUT MORE?

Our social media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Close Date: 12/05/2026

Date Posted

05-May-2026

Closing Date

12-May-2026

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.