US Oncology Medical Affairs - Medical Lead - Breast Cancer

The opportunity 

As Medical Lead, Breast Cancer within US Oncology Medical Affairs, you will serve as a medical and scientific leader for the breast cancer portfolio, including the ADC franchise. You will lead the development, alignment and execution of the US medical strategy, provide medical leadership to the Core Medical Team, and partner across US and global functions to translate scientific priorities into meaningful outcomes for patients, healthcare professionals and the broader healthcare ecosystem. 

This is an opportunity for an experienced physician or doctorate-level medical affairs leader who combines deep oncology expertise with strong business acumen, launch experience and the ability to influence across complex, cross-functional networks. 

Why join us 

• Meaningful patient impact: help shape evidence, education and medical strategy in breast cancer, with patient needs at the center of decisions. 

• Science with scale: work across an innovative Oncology portfolio and collaborate with leading internal experts, external scientific leaders, academic institutions, professional societies, advocacy organizations, payers and providers. 

• Leadership with ownership: set direction, make evidence-based decisions, lead through influence and take accountability for high-impact medical plans, launches and investments. 

• Growth and development: expand your expertise through cross-functional and global collaboration, exposure to the product lifecycle, and opportunities to mentor Medical Affairs colleagues. 

• Inclusive, collaborative culture: join a team that values diverse perspectives, constructive challenge, curiosity and speaking up. 

• A connected scientific campus: work on-site in Gaithersburg, a major US R&D and Oncology campus designed to encourage collaboration and cross-functional science. 

What you will do 

• Lead US Medical Affairs activities for breast cancer and provide medical leadership to the Core Medical Team. 

• Contribute to integrated medical plans and translate strategic imperatives into clear, measurable tactics for the disease area and brands. 

• Own the alignment and execution of medical plans, launch plans, resources and budgets in partnership with US commercial, global and functional teams. 

• Ensure the medical accuracy, scientific integrity and fair balance of promotional, medical information and learning materials for internal and external audiences. 

• Shape evidence-generation priorities with global partners, including medical evidence plans, Externally Sponsored Scientific Research, HEOR studies and outcomes research. 

• Build trusted peer relationships with external scientific experts, academic institutions, professional societies, advocacy organizations, payer and provider groups. 

• Lead or contribute to national and regional advisory boards, congress activities, scientific exchange and speaker training. 

• Provide medical input to product safety in collaboration with Patient Safety physicians. 

• Partner closely with Medical Science Liaisons and National Clinical Account Managers to support key accounts appropriately. 

• Align the US strategy with the Global Medical Affairs Leader and other global stakeholders. 

• Guide and mentor Medical Affairs colleagues, sharing expertise and raising scientific and strategic capability across the team. 

What you bring 

Essential requirements 

• Doctorate degree in Medicine (MD or DO), PhD, PharmD or equivalent, with relevant experience. 

• At least 5 years of related experience in the biopharmaceutical industry, clinical practice or a research institution.
• 1-3 years in Headquarters base Medical Affairs role
• 1-3 years of experience supporting oncology in a country, regional or global organization. 

• Demonstrated ability to develop and execute medical strategy, work across the product lifecycle and support launch planning. 

• Strong business acumen

• Proven ability to collaborate productively with scientific, medical, commercial, market access and other cross-functional partners. 

• Strong written, verbal, presentation, and stakeholder-influence skills. 

• Ability to travel nationally and internationally up to approximately 10%. 

Desirable requirements 

• Direct experience in breast cancer
• Proven understanding of FDA requirements

• Knowledge of relevant professional societies and established relationships with scientific and medical experts. 

• Experience with pharmaceutical drug development, evidence generation, HEOR and medical/scientific affairs. 

About our Gaithersburg campus 

Our Gaithersburg, Maryland campus is a major home for R&D and Oncology in the US, located near Washington, DC. The modern scientific environment brings together specialists, technology and collaborative workspaces to support cross-functional science. Site amenities include a fitness center, employee healthcare clinic, electric vehicle charging stations, a full-service cafeteria, dry cleaning and activity-based workspaces designed for different working styles. 

Compensation and benefits 

The annual base pay range for this position is $193,281 - $289,922 USD. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).

Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans.

Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

Ready to make a meaningful impact? 

If you are energized by scientific challenge, motivated by the opportunity to improve outcomes in breast cancer, and ready to lead across medical, commercial and global partnerships, we would welcome your application. 

Connect with AstraZeneca 

LinkedIn: https://www.linkedin.com/company/1603/ 

Facebook: https://www.facebook.com/astrazenecacareers/ 

Instagram: https://www.instagram.com/astrazeneca_careers/?hl=en 

AstraZeneca is committed to fostering an inclusive culture and a workplace where diverse perspectives are valued.

Date Posted

05-Oct-2026

Closing Date

18-Oct-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.