Sr. Scientist, Translational Proteomics, Biomarker Science and Technologies

The Sr. Scientist Translational Proteomics develops proteomics technologies, validates protocols, and analyzes data for biomarker research. The role operates LC-MS instruments, collaborates across teams, and ensures compliance with scientific regulations.

Typical Accountabilities

• Develop MS-based proteomics technologies for clinical biomarker studies to ensure robust translational research.
• Validate and implement protocols for processing clinical samples, including tissue and plasma, following SOPs.
• Generate and maintain PRM and DIA data to support clinical studies and collaborate with bioinformatics teams to confirm biomarker clinical utilities.
• Operate LC-MS instruments, apply strict QC measures, conduct routine maintenance, and adopt new technologies to enhance protocols.
• Analyze data, summarize outcomes, and present findings at functional and project reviews to streamline decision-making processes.

Education, Qualifications, Skills & Experience

Essential

• Bachelor's degree in a scientific discipline
• Relevant experience in the pharmaceutical industry and early drug development phases of the drug development process
• Comprehensive understanding of current principles and concepts within the role-specific field
• Familiarity with regulations and compliance systems related to scientific work; Broad understanding of R&D disciplines; Awareness of patent and intellectual property issues
• Ability to work independently and collaboratively; Excellent communication skills.

Desirable

• Master’s degree in a related field
• Advanced knowledge in the subject area
• Advanced degree within the field and/or professional certification
• Well-developed understanding of drug metabolism processes and pharmacokinetics
• Well-developed understanding of the creation of biosignatures and biomarker analysis.

The annual base pay for this position ranges from $116,284.00 - $174,426.00. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

19-Aug-2026

Closing Date

04-Sep-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.