Senior Scientist, Cell Therapy

Senior Scientist, Cell Therapy

Gaithersburg, MD

Are you ready to make a significant impact in the field of Oncology? We are seeking a highly-motivated and independent Senior Scientist with proven experience in Cellular Therapy, Immunology, and/ or Immuno-Oncology to join our rapidly growing Cell Therapy Team. This is your chance to be at the forefront of innovative Cell Therapy products, designing and conducting laboratory experiments, developing methodology, and generating and interpreting scientific data in a highly collaborative environment.

Accountabilities:

As a Senior Scientist, you will conduct routine drug discovery research experiments by applying the techniques of molecular and cellular biology. You will also be responsible for conducting hands-on in vivo research including design, implementation, and interpretation of studies. Your role will involve supporting a team and working collaboratively with project managers to ensure the efficient relay of information and forward translation of data. You will assess and report data, with little or no guidance, in a clear and concise manner, while developing an understanding of its implications within the overall context of drug discovery.

Essential Skills/Experience:

• PhD in a relevant subject area with 0-3 years of demonstrated experience in Cellular Therapy, Immunology, and/ or Immuno-Oncology
• Well-developed understanding of molecular and cellular biology, immunological assays, and cell transfection/ transduction
• Extensive in vivo skillset including animal handling, mouse tumor models, standard routes of dosing and engraftment, and tissue processing or comprehensive in vitro skills
• Ability to design, execute, and troubleshoot experiments, and to review, analyze, and interpret results
• Advanced cell culture techniques

Desirable Skills/Experience:

• Experience with genome editing technologies (CRISPR/ Cas9, base-editing, transposons, etc.)
• Multicolour flow cytometry
• In vitro and in vivo experience with murine T cells
• Basic experience developing cellular therapies including CAR-T/ CAR-NK, TCR-T, and/ or TIL therapies
• Experience generating and analyzing single cell RNAseq and ATACseq datasets
• Background in drug discovery and development in the pharmaceutical industry

At AstraZeneca's Oncology R&D department, we are dedicated to following the science. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. We are pioneers making bold moves that transform the way cancer is treated and truly improve patient outcomes. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. It's science with an impact-making a difference for patients and people around the world.

About Our Gaithersburg Oncology Hub

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center, game rooms, community garden and more. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams.

So, what’s next?

Are you ready to join a team that is committed to pushing the boundaries of science to change the practice of medicine? Apply today!

If you’re curious to know more, please contact Bobbi Poole, our Talent Acquisition Partner.

Closing Date: September 10, 2024

Competitive remuneration and benefits apply

We offer a competitive Total Reward program including a market driven base salary, bonus and long term incentive. We have a generous paid time off program and a comprehensive benefits package.

Where can I find out more-

Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We follow all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.