Senior Manager, IO Forecasting

Position Summary:

Senior Manager, IO Forecasting leads the US forecasting process for a key tumor type within the US Immuno-Oncology portfolio. As a thought partner to the business, the Senior Manager will develop product-specific short-term and long-term forecasts and provide critical insights into market risks & opportunities that may impact performance to ultimately guide commercial strategy and decision-making. Strong analytical and critical thinking skills are essential to developing rigorous forecasts using patient-flow / patient-based models and incorporating new AI capabilities. The Senior Manager seamlessly collaborates with Insights and Analytics colleagues to deliver fact-driven, actionable insights to the business. In addition, the Senior Manager will closely partner with Marketing, Sales, Market Access, Sales Operations, Global Analytics & Insights, Supply Planning, and Finance to ensure alignment on forecast assumptions and narrative. The Forecasting Senior Manager regularly presents to senior leaders the forecast and performance story.

Abilities key to this position include consultative and influencing skills, quantitative technical skills, and proficiency in interpreting primary market research / secondary data analyses.

This role reports to the Franchise Director, IO Forecasting and Performance and sits within US Integrated Insights - Oncology Business Excellence organization, an inclusive team that partners with the US Oncology commercial organization to drive strategic decisions by providing objective, data-driven insight generation and analytics.

Roles & Responsibilities:

• Lead the US forecasting and business planning processes and all associated work streams for covered brand / indications (scenario planning, integration with Finance, etc.)
• Develop, build, and maintain up-to-date product-specific short-term and long-term forecasts models, synthesizing an integrated picture with information across multiple sources; as required, manage external agency executing the model build/update
• Proactively and clearly identify key drivers that impact short-term and long-range product and market forecasts, highlighting significant risks and opportunities
• Incorporate AI analytical tools into the forecast process and support continuing development of the AI forecasting platform
• Collaborate cross-functionally with key commercial leaders, Business Excellence colleagues, and other forecast stakeholders to align on objective, data-driven forecast inputs
• Provide in-depth analyses of underlying drivers of brand performance in support of key business deliverables and milestones (e.g. Quarterly Business Reviews)
• Monitor external environment to stay up to date on the competitive landscape and latest market developments for covered brand/indications
• Consult on primary research and secondary analytics relevant to forecasting, and incorporate results into modeling to add deep customer insight and assess future events
• Deliver insightful, objective presentations to senior leaders (e.g., VP of US IO Franchise) that clearly and succinctly highlight critical insights and business implications through strong storytelling
• Essential Experience/Qualifications
• Bachelor's degree, with a preference for a quantitative field (e.g., Engineering, Data Science, Statistics, Math, Economics, Computer Science, Operations Research)
• 2+ years of experience at a pharmaceutical / biotechnology manufacturer or working in the biopharmaceutical industry (e.g., forecasting, data/analytics, management consulting, market research, investment banking)
• 2+ years of experience in forecasting: building models, leading input evaluation, communicating outputs, and guiding business decisions; Preferably some experience in a biopharmaceutical role
• Familiar with pharmaceutical data sources (APLD, IQVIA, claims, etc.) and epidemiological data (SEER, Kantar, DRG)
• Occasional travel may be required
• Desired Experience/Qualifications
• Advanced Quantitative Degree or Advanced Marketing Degree (e.g., MBA)
• Experience working in Oncology
• Knowledge of primary market research, advanced analytics, and competitive intelligence; experience collaborating with others to integrate findings into the forecast

Leadership Capabilities:

Passion for Customers: Understands one's customers and uses that insight to provide value; Highly consultative with ability to build credibility and relationships with key stakeholders.

Thinks Strategically: Strategic and critical thinking skills to quickly identify and act on opportunities, combining forethought with action.

Acts Decisively: Makes and acts on decisions quickly and effectively and fosters the same in others; Comfort with ambiguity with the ability to challenge traditional thinking and courage to take smart risks to solve problems.

Works Collaboratively: Actively creates and promotes cross-boundary collaboration to achieve better business results.

Ability to influence: Strong communication and influencing skills with demonstrated ability to develop and effectively present succinct, compelling reviews of business performance infused with insight and business implications/actions to be considered.

Lead without authority: Demonstrated success in mentoring, coaching, directing others towards delivering towards a shared goal, even without direct reporting lines; Creates an environment that enables others to perform at their best.

The annual base pay for this position ranges from $ 147,908.00 - 221,862.00. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

12-Aug-2026

Closing Date

26-Aug-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.