Senior Global Clinical Operations Program Director, Late Development Oncology

At AstraZeneca, we push the boundaries of science to change the practice of medicine and transform the lives of patients living with cancer. We are a science-based, leading and decisive Oncology enterprise united in our vision to eliminate cancer as a cause of death. With one of the broadest and deepest Oncology pipelines in the industry, there are many opportunities to work with new and novel drugs and help discover what's next. We foster a mindset of courage, where everyone is empowered to step up, innovate and work at pace. We lead through true collaboration, building collective wisdom by giving everyone a chance to input. It's science with an impact-making a difference for patients and people around the world.

Are you ready to make a difference? Apply now and join us in our mission to eliminate cancer as a cause of death!

Introduction to role:

Join us as a Senior Global Clinical Operations Program Director (Sr GPD) in our Oncology R&D department. This core global role within the Clinical Operations function of Late Stage R&D is accountable to the Global Product Team (GPT) for the operational delivery of the agreed clinical development plan. As a Sr GPD, you will be responsible for program leadership and management of all clinical operations deliverables to scope, quality, budget, time, resource and risk, ensuring new innovative design and delivery models are used appropriately.

Accountabilities:

As a Sr GPD, you will be accountable for oversight of all clinical program activities, ensuring relevant issues are escalated to GPT. You will partner effectively with the Global Clinical Head (GCH) and the Biometrics Team Leader to provide leadership, clear direction and aligned goals to the CPT members/clinical delivery teams. You will also be responsible for establishing team structure and ways of working to ensure CPT is a high performing team. Additionally, you will be accountable for the clinical operations component deliverables of regulatory submissions, providing support for regulatory interactions and reports and clinical contributions to inspection readiness.

Essential Skills/Experience:

• Bachelor of Science/Master of Science degree in related discipline, or equivalent work experience. Advanced degree is preferred

• 12 years of relevant experience

• Extensive global drug development leadership or equivalent leadership experience demonstrated in a variety of roles.

• Extensive experience across the product life cycle with experience in late stage development and ideally across multiple therapeutic areas

• Clinical operations knowledge with strong track record of delivery

• Comprehensive knowledge of the clinical and pharmaceutical drug development process

• Proven ability to develop programs to meet business goals and to assess business risk versus potential value; ability to understand global business requirements

• Significant experience of program management and use of project management techniques in complex projects, including resourcing, financial management and business case development

• Proven ability to develop successful collaborations with internal stakeholders and external partners

• Strong strategic influencing skills: ability to influence broadly within and outside the organisation

• Excellent written and verbal communication skills

• Proven teamwork and ability to work collaboratively across a wide range of disciplines

• Track record of planning, prioritisation and delivery success

• Willingness to travel both domestic and international

Desirable Skills/Experience:

• Demonstrated ability to drive process improvement and/or functional work

• Experience of implementing changes in ways of working that focus on increasing efficiency

• Regulatory submission experience

• Previous success of working in Japan and China to ensure delivery of global programmes to meet business needs

• Proven experience in leading teams through change

• Experience of and insight into the Clinical environment to be able to drive major improvement programs

• Experience in line management of leadership roles

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Become part of our outstanding and ambitious world.

The annual base pay (or hourly rate of compensation) for this position ranges from $233,586.40 - $350,379.60 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Why AstraZeneca

Here you will join a scientific community that blends academic insight with real-world delivery, partnering with leading centers around the globe to tackle some of the hardest-to-treat cancers. You will work across a broad, high-quality pipeline backed by meaningful investment and modern technology, surrounded by teammates who share knowledge openly and value kindness alongside ambition. Your leadership will be felt at scale—accelerating pivotal studies, shaping regulatory strategy and helping bring life-changing medicines to patients faster—while you continue to grow through diverse collaborations and hands-on impact.

If you are ready to lead global programs that set new standards in cancer care and leave a measurable legacy for patients and your career, send us your profile today!

Date Posted

29-Jun-2026

Closing Date

11-Jul-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.