Global Product Leader - Calquence

At AstraZeneca we turn ideas into life changing medicines. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world. We commit to those areas where we think we can really change the course of medicine and bring big new ideas to life.

As complex, senior and highly visible roles in our company our GPLs are aligned to, and responsible for, the stewardship of leading medicines in our portfolio. They are responsible for leading the cross-functional Global Product Team to deliver the integrated global product strategy, inclusive of clinical development, medical, regulatory and integrated commercial plans.

What you’ll do

The key accountabilities include:

• Lead the Global Product Team (GPT) which together defines and drives the strategic direction of the medicine, ensuring scientific value creation across the lifecycle including clinical development, regulatory approvals, product launch/commercialization and lifecycle management.
• Is the single point of contact for the asset, working in collaboration with a cross-functional GPT and disease strategy teams within R&D.
• Is accountable for the assigned asset or indication strategy and its execution including Target Product Profile (TPP), investment decisions and agreements with the business
• Ensures cross-functional alignment of Development, Commercial and Operational strategies and delivery of the indication (or asset) clinical program
• GPL is accountable and endorses recommendations on behalf of the GPT, while GPT members may have responsibility for key deliverables (e.g. PTRS)
• Elevates identified risks/opportunities for indication program to Franchise Team / LSPC
• Is a role model and an ambassador for the brand and for AZ with our internal partners and external collaborators, with representatives from the scientific community and health authorities, and in any interactions with health care practitioners and patients.
• Is entrepreneurial in problem solving and maximizes opportunities for the brand through shaping and driving ambitious and deliverable product strategy
• Ensures appropriate Governance and Compliance and protects AZ’s Rights, Data and Intellectual Property
• Builds and effectively leads high performing cross-functional teams.
• Speak up and challenge, always towards better outcomes and towards integrity, enabling growth of the organization, team and individuals.
• Enthusiastically embrace the diversity of healthcare ecosystems as significant opportunity
• Relate and connect deeply with various KEES, healthcare systems and large markets in order to deliver direction and support.

Essential for the role

• Education: Ph.D. or masters in life sciences
• 15+ years of pharmaceutical experience including in depth Haematology knowledge
• Global cross functional leadership, ideally in both global R&D and commercial or medical setting
• Inspirational, empowering leader in a strategic multifunctional environment
• Strong decision-making capabilities and understanding how to work with a cross-functional teams to gather appropriate inputs, challenge ideas, and come to clear decisions
• Excellent scientific and clinical acuity – understands the full value change of medicine and translational science
• Has influenced significant functional investment decisions.
• Encouraged and influenced without direct authority to deliver positive patient outcome.
• Has led sophisticated projects with ambitious achievements in fast paced circumstances
• Proven track record of achieving results through others, as well as coaching and developing impactful team members.

Desirable for the role

• Scientific or medical degree, potentially coupled with marketing or commercial experience and/or degrees.
• Sub-team leader and worked in a Global Product Team (Early or Late stage) as a core team member
• Drug development and regulatory/filing experience

The annual base pay for this position ranges from $216,800 to $325,200. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. ​

Date Posted

14-Jan-2026

Closing Date

29-Jan-2026

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.