Director, Clinical Pharmacology & Quantitative Pharmacology (CPQP)- Oncology
Introduction to the role:
At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, thenyou’reour kind of person.
Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our Gaithersburg office3 days a week. Our headofficeispurposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects. Our dedication to sustainability is also central to our culture and part of what makes AstraZenecaa great placeto work. We know the health of people, the planet and our business are interconnected which is whywe’retaking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention.
This is a strategic and scientific job accountable for providing the scientific quality of clinical pharmacology program performed within Oncology. This person will apply state of the art Clinical Pharmacology and Model-Informed Drug Development (MIDD) approaches to influence designs and internal/external decision making across the portfolio. The individual will closely with Oncology TA lead and discipline lead to provide strategic and technical advice, support global initiatives to develop the clinical pharmacology discipline and serve as a global reviewer and mentor to junior staff. The incumbent will work closely with colleagues across Innovative Medicines, Global Medicines Development and other AZ units to ensure implementation of clinical pharmacology/ MIDD and to drive a QCP program across the business.
Accountabilities:
- Accountable for developing a culturesupportive of MIDD approacheswithin theOncologyinfluencing key partners,stakeholdersand regulatorsof its value and application(L)
Accountable forplanning andexecutingstate-of-the-artclinical pharmacology approacheswith direct value for projects cross the portfolioincluding go/no go decision making(T)
Scientific and strategic input into pre-clinical, clinical, and post-approval development plans(S, T)
Accountable for oversight, support and delivery of scientific and strategicclinical pharmacology plans relatedtoOncologyin both early and late development(S, T, D, L)
Support evaluation of candidates for in/out-licensing(S, T, D, L)
Contribution tothe identification and developmentof drug-disease modelsandothermodelling approachesto support internal and external decision making in collaboration with internal and external partners (when relevant) (S,D,L)
Support theOncologyand Discipline lead in development of strategy, in scientific operations and business management(S, T, L)
Accountableto provide peer review and mentoring within and acrossTA’s(S, T, L)
Support and contribute to the development of theClinical PharmacologyDiscipline in terms ofprovidingtraining and knowledge sharing(S, T, D, L)
Monitoring external and internal environment in terms of relevantnew methodologies and applications(T, D)
Increase AZ profile externallyin the area ofclinical pharmacology/MIDDby speaking at externaleventsand bypublication in recognized external journals(L)
Ensure AZclinical pharmacology plansare aligned with current regulatory expectation (T)
Essential skills/experience:
Expert knowledge of pharmacokinetics and Model-InformedDrug Development (T)
Demonstrated broad translational and clinical developmentexpertiseand experience exemplified byat least10years international drug development experience, with emphasis onClinical Pharmacology
PhD degree preferred or equivalent (M.Sc./Pharm.D. as minimum requirement) with relevant experiencerequired
International scientific reputation gained from scientific publishing in the field onDMPK/Clin Pharm/MIDD (T,D,L)
Demonstrated ability toidentify,developand executeclinical pharmacologyactivities at level of portfolio (S)
Excellent oral and written communication skills
A demonstrated knowledge ofglobalregulatory, compliance, processes,standardsand issues specific toclinical pharmacology(T)
Strong leadership capabilities,in particular withregards to influencing skills(L)
Experience in mentoring and developing others (L)
Training and experience with PK software (Phoenix,WinNonlin)
Desirable Skills/Experience:
Experience in several organisations
Early and late phase clinical development experienceincludingregulatory filing(NDA, MAA)
Experiencewith relevant software and tools within the field of MBDD(e.g.SIMCYP, R, NONMEM)(T)
Experience working on ADCs and Radio conjugates
The annual base pay (or hourly rate of compensation) for this position ranges from $179,172.80 to 268,759.20 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.
Why AstraZeneca:
Join a place where you are trusted to take ownership and move fast, combining scientific rigor with data-driven operations to deliver therapies that change lives. You will work shoulder-to-shoulder with unexpected teams in the same room, unleashing bold thinking to solve complex logistics challenges at scale. We champion curiosity and decisive action, value kindness alongside ambition, and empower you with the tools, partnerships, and freedom to shape how living medicines reach patients across the world.
Call to Action:
Lead the global nerve center of cell therapy logistics and build the systems, teams, and partnerships that move cures to patients faster—bring your expertise and make your mark.
Where can I find out more?
Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
#LI-Hybrid
Date Posted
26-Mar-2026Closing Date
19-Apr-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.
Gå med i vårt talangnätverk
Bli först med att få jobbuppdateringar och nyheter från AstraZeneca
Registrera
