Evidence Generation Lead BBU& OBU

Job Title: Evidence Lead BBU & OBU

Location: Dublin

Competitive salary and bonus

Introduction to role:

Are you ready to turn real-world evidence into decisions that change clinical practice and accelerate patient access? In this role, you will lead evidence generation across two of our most impactful portfolios, shaping value stories that inform development, access, and adoption. You will connect science, data, and strategy so that every study, model, and analysis moves us closer to better outcomes for patients and a stronger, more competitive business.

You will collaborate across clinical, medical, market access, and commercial teams to co-create evidence plans that matter—from transforming care initiatives to fit-for-purpose studies that resonate with regulators and payers. How would you translate complex data into compelling insights that guide product strategy and market decisions at scale?

Accountabilities:

- Evidence Strategy and Planning: Evaluate and analyze information to generate high-quality RWE input to target product profiles, target product claims, and value demonstration plans; contribute to study roadmaps and resolve complex issues that influence market access decisions and product evidence needs.

- Program Leadership and Management: Lead RWE activities and adjacent projects, including departmental training and administrative responsibilities, ensuring clarity on priorities, resources, and delivery.

- Capability Building and Training: Train cross-functional partners on the role and application of RWE, elevating literacy and adoption across the organization.

- Study Oversight and Methodology: Supervise study teams in patient-reported outcome instrument development and administration, as well as model development, ensuring methodological rigor and decision relevance.

- Vendor and Partner Management: Prepare requests for proposals for RWE projects, lead vendor selection, and manage delivery with academic collaborators and clinical research organizations to time, budget, and quality for both RWE and other evidence projects.

- Regulatory and HTA Readiness: Support writing, referencing, and development of reimbursement and formulary dossiers; prepare RWE data as background materials for registration packages; lead preparations for regulatory interactions and participate as needed.

- External Data and Methods Excellence: Advance knowledge in health economics and the impact of pharmaceutical product development; identify and qualify external RWE data sources and literature to expand our evidence ecosystem.

- Culture and Leadership: Model courageous leadership, creativity, and collaboration; mentor teams to raise the bar on evidence quality and impact.

- Compliance and Governance: Ensure and monitor compliance among team members and third parties by reinforcing codes, policies, and standards; ensure completion of required training; foster an open culture for questions and concerns; promptly address and report non-compliance.

 Essential Skills/Experience:

- Master Degree in (Bio)Medical Science

- Thorough knowledge or experience of the pharmaceutical industry and the area of field medical liaisons

- Knowledge of legislation relevant to pharmaceutical sales and marketing

- Competencies: Balances stakeholders; Collaborates; Customer focus; Decision quality; Drives results; Ensuring accountability; Situational adaptability; Strategic mindset; Communicates effectively; Proactivity

- Managerial competencies: Direct works; Drives engagement

Desirable Skills/Experience:

- Advanced degree (e.g., PhD, PharmD, MPH) in epidemiology, outcomes research, biostatistics, health economics, or related field

- Proven leadership of multi-country RWE programs spanning design, execution, and dissemination, including registries, external control arms, or pragmatic and hybrid studies

- Hands-on experience with patient-reported outcomes, preference studies, economic modeling, and methods to minimize bias and confounding in observational research

- Strong track record in HTA/payer engagement and development of reimbursement or formulary submissions

- Familiarity with real-world datasets and governance (claims, EHR, registries, digital health), and analytic tools or languages (e.g., R, SAS, Python) in partnership with data science teams

- Effective vendor and alliance management across CROs, academic partners, and data providers

- Experience collaborating across clinical development, medical affairs, and commercial teams to align evidence with product strategy

- Publication record demonstrating impact on clinical practice, access, or policy

- Therapy area experience across cardiovascular, renal, metabolism, respiratory, immunology, and oncology is an advantage

- Experience leading transforming care initiatives and evidence programs that inform care pathways and system-level outcomes

Why AstraZeneca:

Here you will work where science, technology, and market insight meet to reshape patient care—fast. We bring unexpected teams into the same room to unleash bold thinking, joining clinical experts, data scientists, policy leads, and market shapers to co-create evidence that matters. You will enjoy the resources of a global leader with the pace and ownership of a focused, agile environment, all grounded in a patient-first mindset. We value kindness alongside ambition, offer constant feedback and learning, and open doors across therapy areas as we advance an expanding pipeline and redefine standards of care.

Call to Action:

If you are ready to lead evidence that moves decisions, markets, and medicine, step forward and make your mark today!

Date Posted

13-Jul-2026

Closing Date

26-Jul-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.