Senior Manager – IoT Platform

Job Title: Senior Manager – IoT Platform

GCL: E

Introduction to role:

Are you ready to architect a global IoT platform that powers manufacturing, quality, and supply operations to deliver medicines to patients faster and with greater reliability? This role puts you at the center of how we connect equipment, data, and processes across sites to drive real-world outcomes—reducing downtime, improving product quality, and accelerating supply to those who need it.

You will lead the strategy and delivery of a modern, secure, and highly available IoT platform, integrating edge data with enterprise systems to unlock value at scale. In this environment, you will be empowered to take ownership, challenge the status quo, and push boundaries with cloud-native services, event-driven patterns, and robust governance. If you grow with building partnerships, orchestrating sophisticated integration, and elevating performance through data and automation, this is your moment.

Accountabilities:

• Take charge of the complete IoT platform strategy and reference architecture. Ensure scalability, security, and high availability. Align with enterprise standards to deliver measurable outcomes in manufacturing, quality, and supply chain.
• SAP Integration and Enterprise Connectivity: Design and govern seamless integration between IoT platforms and SAP (S/4HANA, ECC, SAP BTP), enabling reliable flows to SAP PM/EAM, PP/QM, and MII/ME/DM; define patterns using APIs, events, and middleware to ensure transactional integrity and data consistency that supports business-critical processes.
• Cloud and Infrastructure Architecture (AWS): Architect and govern AWS-based IoT infrastructure across IoT Core, compute (EC2, EKS, Lambda), storage (S3, EBS), and networking (VPC, VPN, Direct Connect); drive multi-account strategies, security baselines, resilience, disaster recovery, performance, and cost optimization in partnership with enterprise cloud teams.
• Data Platform and Database Administration: Be responsible for the collection, retention, and transformation workflows for time-series and relational data, data lakes, and analytics platforms; define data models, retention policies, and tuning strategies that ensure data quality, availability, and compliance.
• Platform Operations and Run Excellence: Own day-to-day operations including monitoring, alerting, handling system resources, performance management, patching, and upgrades; define and handle SLAs, SLOs, and important metrics; implement ITSM-aligned processes (incident, problem, change) and drive continuous improvement.
• Guide and support system designers, developers, infrastructure specialists, and operations while building and scaling teams with a balanced mix of internal talent and partners. Handle vendors and system integrators. Ensure predictable delivery across build, run, and improvement streams.
• Build and uphold platform blueprints, patterns, and reusable assets. Establish governance models for onboarding new use cases and sites. Review and approve solution builds to ensure compliance and effective information exchange.
• Security, Compliance, and Risk Management: Guarantee that the platform aligns with enterprise security, data privacy, and regulatory standards (including GxP where applicable); implement identity, access, and network security controls; support audits, risk assessments, and remediation activities.
• Collaborator Engagement: Partner with manufacturing, quality, operations, engineering, enterprise architecture, security, cloud, SAP CoE, data and analytics teams, and external vendors/system integrators to align roadmaps and deliver sustained business value. How will you translate complex requirements into secure, scalable solutions that improve performance across multiple sites?

Essential Skills/Experience:

Platform Strategy & Architecture

Be responsible for the overall IoT platform architecture, ensuring scalability, security, and high availability.

Define reference architectures, blueprints, and design standards for IoT solutions.

Lead solution architecture for sophisticated IoT use cases across manufacturing, quality, and supply chain.

Drive alignment with enterprise architecture, security, and data standards.

SAP Integration & Enterprise Connectivity

Design and govern end-to-end integration between IoT platforms and SAP (SAP S/4HANA, ECC, SAP BTP).

Enable integration with:

SAP PM / EAM

Sap pp / qm

SAP MII / ME / DM (where applicable)

Define integration patterns using APIs, events, and middleware.

Ensure transactional integrity and data consistency between IoT and SAP systems.

Cloud & Infrastructure Architecture (AWS)

Architect and govern AWS-based IoT infrastructure, including:

AWS IoT Core

Compute (EC2, EKS, Lambda)

Storage (S3, EBS)

Networking (VPC, VPN, Direct Connect)

Define multi-account strategies, security baselines, and cost optimization.

Ensure resilience, disaster recovery, and performance of the platform.

Collaborate with Cloud and Infrastructure teams on enterprise standards.

Data Platform & Database Administration

Be responsible for IoT data ingestion, storage, and processing pipelines.

Handle databases including:

Time-series databases

Relational databases

Data lakes and analytics platforms

Define data models, retention policies, and performance tuning strategies.

Ensure data quality, availability, and compliance with regulatory requirements.

Platform Operations & Run

Own day-to-day platform operations (“run”) including:

Monitoring, alerting, and incident management

Planning resource needs and managing performance

Patch management and upgrades

Define and manage SLAs, SLOs, and KPIs.

Implement ITSM-aligned processes (incident, problem, change).

Drive continuous improvement and operational excellence.

Team Leadership & Delivery Management

Lead and mentor teams with multi-functional roles including architects, engineers, DevOps, and operations.

Build and scale teams with the right balance of internal talent and partners.

Handle vendor and system integrator relationships.

Ensure predictable delivery across build, run, and enhancement streams.

Blueprinting & Governance

Create and maintain platform blueprints, patterns, and reusable assets.

Establish governance models for onboarding new use cases and sites.

Review and approve solution designs to ensure compliance with standards.

Drive documentation, collaboration, and effective methods.

Security, Compliance & Risk Management

Ensure platform compliance with enterprise security, data privacy, and regulatory standards (e.g., GxP where applicable).

Implement identity, access management, and network security controls.

Support audits, risk assessments, and remediation activities.

Key Stakeholders

Manufacturing, Quality, Operations, and Engineering teams

Enterprise Architecture, Security, and Cloud teams

SAP CoE and Data & Analytics teams

External vendors and system integrators

Desirable Skills/Experience:

Experience with industrial connectivity and edge technologies (e.g., MQTT, OPC UA, Modbus, industrial gateways) and device management at scale.

Expertise in event streaming, messaging, and data processing (e.g., Kafka, Kinesis, IoT rules engines) and designing event-driven architectures.

Hands-on background in DevOps and automation for IoT platforms (CI/CD, IaC with Terraform/CloudFormation, observability with CloudWatch, Prometheus/Grafana).

Deep understanding of manufacturing execution and shop-floor systems integration patterns; experience deploying across multiple sites and regions.

Familiarity with SAP BTP services for integration and extension; practical experience with SAP data models supporting EAM/PM, PP/QM, and related modules.

Strong grounding in security-by-design, zero-trust principles, and regulated environments; prior experience with GxP validation and audit readiness.

Proven track record of vendor and partner management, commercial negotiation, and outcome-based delivery; experience with Agile methods and scaled governance.

Relevant certifications (e.g., AWS Solutions Architect, TOGAF, SAFe) and evidence of continuous learning through hackathons, community contributions, or open-source work.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge

perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Why AstraZeneca:

Here, technology fuels discovery and delivery. You will join a community of entrepreneurial builders who pair scientific curiosity with modern engineering to unlock the potential of data, AI, and automation at global scale. We bring unexpected teams together to spark bold ideas, back them with investment and coaching, and turn them into practical solutions that help reach patients sooner. We value kindness alongside ambition, encourage experimentation through events like hackathons, and support you to shape your path while contributing to something bigger—transforming how medicines move from lab to life.

Call to Action:

Step into this role to architect and lead a world-class IoT platform that accelerates impact for patients—seize the opportunity and put your expertise to work today!

Date Posted

04-Feb-2026

Closing Date

11-Feb-2026

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.