Scientist, (in vivo) - Clinical Immuno-Oncology Discovery, Early Oncology

Job Title: Scientist, (in vivo) -  Clinical Immuno-Oncology Discovery, Early Oncology, Cambridge UK

Location: Cambridge

Salary:  Excellent

Introduction to role:

Be part of the team that follows the science to transform the lives of cancer patients.  As part of Early Oncology Research and Development, you will be a member of a team of professionals who are pioneering new frontiers by identifying and treating patients earlier while working toward the aim of eliminating cancer.  We are driven by curiosity and backed by billions of investment pounds, we are empowered at every level to follow the science in pioneering new frontiers, exploring the most complex Oncology challenges to deliver new molecular entities over and over again.  AstraZeneca’s pipeline is one of the broadest and deepest in the industry.  Why don’t you consider joining an unrivalled scientific community filled with the brightest, curious and diverse minds?  

Are you a highly motivated Scientist with significant hands-on in vivo expertise and practical knowledge of murine tumour models? If so, we invite you to join the Clinical Immuno-Oncology Discovery (CIOD) Team at AstraZeneca. In this role, you will contribute to the advancement of innovative Clinical Immuno-Oncology products by conducting vivarium-based laboratory experiments, developing methodology, and generating and interpreting scientific data in a highly collaborative environment. This is your chance to learn and grow from the brightest minds in our team with varied strengths where the best of both academia and industry come together to share knowledge, grow together and build significant careers. 

Accountabilities:

• As a Scientist in our team, you will be responsible for conducting and delivering hands-on in vivo research.

• Your work will primarily involve in vivo experimentation allied to specific projects, studies and workstreams.

• You will also have day-to-day responsibility for hands-on delivery of in vivo experiments and data recording.

• You will communicate the results to team members and be involved in the interpretation of data.

• You will also support a team and work collaboratively with project managers to ensure the efficient relay of information and forward translation of data.

• This is a full-time laboratory-based position where you will be performing independent or collaborative delivery of in vivo experiments to address key questions arising from the CIOD Pipeline. 

Essential Skills/Experience:

• At least a BSc/MSc in a biological science (or equivalent professional experience in a relevant subject area), with significant hands-on in vivo experience. 

• Home Office Licence (Modules A-C) or equivalent qualification for animal work. 

• Experience working under Home Office Regulations (as a Personal Licence Holder). 

• Experience working with murine tumour models within the pharmaceutical or biotechnology industry, or in academia. 

• Willingness to undertake hands-on in vivo work in a vivarium laboratory-based role and to work flexibly, including some weekends. 

• Utmost integrity and ethical standards associated with animal experimentation. 

• Significant hands-on experience with animal handling and procedures including tumour models, standard routes of substance administration. 

• Experience with dissection and tissue collection. 

• Strong attention to detail, communication skills, and record keeping. Ability to independently analyse data with appropriate statistical testing. 

• Detailed proficiency in the English language, both writing and speaking. 

Desirable Skills/Experience:

• Experience with humanized mouse models / genetically engineered mouse models of cancer.

• Experience with surgical methods of tumour implantation.

• Drive and enthusiasm for researching approaches to the therapeutic manipulation of the immune system in oncology settings.

• Experience with in vivo imaging methods.

So, what’s next?

Please complete your application before the below closing date (6th March 2025)

We look forward to hearing from you.

Where can I find out more?

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Join us today and be a part of the change!

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.