Pathology Manager in Translational Pathology, Oncology

Job Title: Pathology Manager in Translational Pathology, Oncology

Location: Cambridge

Salary: Competitive

Introduction to role:

Are you ready to make a difference at AstraZeneca? We are seeking a Pathology and Sample Manager to join our Translational Pathology group within the Oncology R&D Cancer Biomarker and Translational Medicine divisions. This is your chance to be at the forefront of translational science evolution for our global oncology group. You'll have the opportunity to impact an industry-leading portfolio, from early clinical development of novel therapeutics to post-marketing opportunities supporting approved targeted therapies. Are you up for the challenge?

Accountabilities:

• Support the operation of the Translational Pathology UK group by assisting leadership with delivery of cancer biomarker portfolio goals.

• Coordinate with leadership team to manage contract workers, including contract pathologists.

• Assist implementation and proper use of the department’s laboratory information management system.

• Draft and update standard operating procedures, work instructions, scoring sheets.

• Maintain up-to-date laboratory staff and contractor training and proficiency records.

• Manage and ensure the portfolio management system (Smartsheet) is current.

• Review department purchasing and accounts to ensure team remains within annual budget allocation.

• Manage cross-charging activities across the portfolio.

• Design and support improvements in scientific or operational approaches and technologies to enhance project quality, efficiency, and effectiveness.

• Contribute to strategic planning and preparation of proposals and business cases.

• Serve as a resource by sharing expertise within and beyond Translational Medicine and Cancer Biomarker Development departments.

• Collaborate with other functions, ensuring effective communication.

• Ensure compliance with Good Clinical Practice, Safety, Health and Environment standards, and all relevant internal AstraZeneca standards and external regulations.

• Generate working instructions and SOPs in line with GCP standards.

• Act as sample owner for commercial human biological tissue samples under the team's remit.

• Procure high-quality human biological tissue and manage storage and usage, building a repository to support our pipeline.

Essential Skills/Experience:

• PhD with exposure in a relevant field.

• PMP certification or equivalent project management experience/training.

• Strong previous pharmaceutical industry experience.

• Experience in histology techniques or working with pathologists.

• Experience in project management, including using project management software such as Asana, Smartsheet, with a demonstrated track record of success in delivering projects on-time and on-budget.

• Strong organizational skills, including good time management skills. Must be highly organized and able to work independently on multiple tasks in a fast-paced environment.

• Takes appropriate initiative and accountability including proactively prioritizing work in alignment with business requirements.

• Experience handling the outsourcing and management of outsourced projects.

• Experienced in using MS Office Suite, especially PowerPoint, Word, and Excel.

• Strong interpersonal and communications skills.

• Familiarity with human tissue tracking software or LIMS.

Desirable Skills/Experience:

• Knowledge of immunohistochemistry (brightfield or fluorescence), microscopy, and carrying out biomarker quantification studies using digital image analysis software.

• Knowledge in one or more AZ portfolio areas: tumour drivers and resistance, DNA damage response (DDR), immuno-oncology (IO), antibody drug conjugates (ADC), and epigenetics.

• Some experience or exposure to microscopy and digital image analysis with software such as HALO or Visiopharm.

• Functional knowledge of FDA Code of Federal Regulations Title 21 Parts 50, 56, 312; Good Clinical Practice for Laboratories; any AZ processes and policies involved in relation to the acquisition, receipt, storage, use, and disposal of human tissue samples.

• Familiarity with cell culture and interpreting Genomics and RNA sequencing data.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

AstraZeneca is where courage meets curiosity! With an ambition to eliminate cancer as a cause of death, we are driven by patient outcomes. Our innovative pipeline is backed by investment aiming to deliver new molecular entities by 2025. We are pioneers of collaborative research, uniting academia and industry to expedite research in hard-to-treat cancers. Here, you can build a rewarding career as part of a team committed to improving millions of lives.

SO, WHAT’S NEXT?

We welcome your application no later than 19th  November 2025

Where can I find out more?

Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/

Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/

Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en

Ready to take action? Apply now to join us on this exciting journey!

Date Posted

11-Nov-2025

Closing Date

19-Nov-2025

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.