Executive Director, US Marketing, Rare Neurology, gMG

For over 30 years, Alexion has been dedicated to transforming the lives of people living with rare diseases. We lead with breakthrough science, deep disease understanding, and an unrelenting commitment to patients. As part of AstraZeneca, we are uniquely positioned to accelerate innovation and reach more patients globally.

Working here means being driven by purpose, acting with integrity, and fostering a culture where people feel valued, connected, and empowered. You’ll join a community that puts patients first, plays to win, and supports your development at every step.

The Opportunity

The Executive Director, US Marketing, Rare Neurology (gMG) will lead the U.S. gMG marketing organization through launch and ongoing portfolio evolution. This high‑impact, high‑visibility role oversees hiring and developing the gMG marketing team, shaping brand strategy, driving lifecycle and competitive readiness, strengthening marketing capabilities, and leading the business planning process.

Success requires the ability to influence without authority, navigate across global and cross‑functional partners, and align diverse interests around a unified U.S. strategy.

What You Will Do

Strategic Leadership & Brand Ownership

• Lead, develop, and coach a high‑performing team across HCP, Patient, Digital, and Marketing Operations.

• Set and execute U.S. gMG marketing strategy and tactics, including disease state education, promotional messaging, non‑personal promotion, patient education, and reimbursement support.

• Drive lifecycle and competitive readiness planning to ensure strong long‑term brand performance.

• Ensure compliant development and execution of all marketing initiatives in close partnership with Legal, Regulatory, and Compliance.

• Lead flawless execution of marketing tactics and programs.

• Bring forward best practices from the global commercial organization and the external market to continually evolve capabilities.

Cross‑Functional & External Engagement

• Build and maintain strong relationships with national and regional gMG key opinion leaders (KOLs).

• Partner with Market Research and engage directly with customers to gain insights and translate analytics into actionable strategies.

• Lead segmentation and targeting approaches that enhance impact across customer groups.

• Work closely with U.S. Sales leadership to implement tactics, review performance, and refine approaches.

• Collaborate closely with Global, Sales, Medical, Regulatory, Clinical, Legal, and the Promotional Review Committee to ensure integrated and aligned execution.

• Manage U.S. promotional budget and oversee external agency and vendor relationships.

• Establish and scale processes for capturing and sharing best practices across the organization.

Marketing Excellence & Business Planning

• Assess functional capabilities and lead efforts to upskill the gMG marketing team.

• Oversee coordinated, cross‑functional planning processes, including annual operating plans, quarterly business reviews, and regional planning—supported by modern tools and approaches that empower regional teams.

Essential Requirements

• Bachelor’s degree in a scientific or business field.

• 10+ years of pharmaceutical or biotech marketing experience.

• Significant commercial leadership experience with demonstrated results.

• Experience leading cross‑functional teams.

• Strong customer orientation across physicians, patients, payers, and major accounts.

• Deep understanding of the U.S. political and access environment.

• Proven track record developing and executing strategies that drive strong commercial outcomes.

• Experience managing agencies, vendors, and promotional budgets.

• Demonstrated leadership, collaboration, and influence in matrixed organizations.

• Strong scientific orientation and ability to engage with complex clinical data.

• Excellent verbal and written communication skills.

• Demonstrated initiative, resilience, and ability to build high‑performing teams.

• Ability to meet the typical requirements of an office‑based environment.

Preferred Qualifications

• MBA.
• Prior sales or sales management experience.
• Experience in hematology, nephrology, and/or rare disease.

This position is based at our Boston, MA campus (US Headquarters for Alexion). When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and bold world.

At AstraZeneca’s Alexion Rare Disease unit, work centers on people living with rare conditions whose journeys demand new thinking every day; this means operating at the edge of science while staying grounded in real patient stories, collaborating across disciplines to turn complex biology into transformative medicines, learning fast in an entrepreneurial environment with the backing of a global biopharma, and growing through tailored development that deepens both leadership capability and empathy for patients and communities we serve.

If this opportunity to redefine what patient engagement can be resonates, apply now to start the conversation!

The annual base pay for this position ranges from $270,221 - 405,332 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

Closing Date

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.