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Senior Scientist, Center for Single Cells Studies, Translational Medicine.

Plats Waltham, Massachusetts, USA Jobb-id R-101756 Datum inlagd 03/02/2021

Senior Scientist, Center for Single Cells Studies, Translational Medicine.

Waltham, MA

At AstraZeneca, we work together across global boundaries to make an impact and find answers to challenges. We do this with the utmost integrity even in the most difficult situations because we are committed to doing the right thing. We continuously forge partnerships that help pursue world-class medicines in new ways, combining our people’s exceptional skills with those of people from all over the globe.  Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. We’re focused on the potential of science to address the unmet needs of patients around the world.  We’re constantly pushing the boundaries of science to deliver life-changing medicines to patients, with a passion for discovery and a pipeline to show for it.

If you’re inspired by the possibilities of science to change lives and you thrive when making brave decisions – join us.

In addition to our passion for the discovery of innovative new medicines, we understand the importance of flexibility in our work-life environment, and we offer a wide variety of benefits, services and programs that provide our employees the resources they need to pursue not only their work goals but also their life goals. We are building a strong research teams that embraces the diversity of talents of team members and allow the larger group to grow and learn together to accomplish our collective goal to improve human health.

Job description

We are looking for a highly motivated senior scientist to join our team at the Center for Single Cell Studies (CSCS), Translational Medicine. The senior scientist will support translational research in clinical and preclinical studies by utilizing single-cell RNA sequencing technologies. The ideal candidate will be highly collaborative, a team player with a strong interest in technology and cancer biology.


  • Planning, preparing and executing procedures of single-cell RNA sequencing using different types of specimens.
  • Optimization of methods for single cell/nuclei RNA sequencing from fresh and archival clinical samples and solve problems during the process.
  • Transition of new technologies from proof-of-concept to standardized workflows
  • Delivery of reliable and high-quality data and metadata to computational analysis.
  • Synergize with scientists, Translational Medicine Leads and computational biologists.


  • Ph.D. in life sciences or related field, with >3 years of experience in hands-on lab work, including tissue dissociation and cell/nuclei isolation.
  • Experience in single cell RNA sequencing techniques including specimen handling, quality control assessments, droplet-based cell processing, library construction and sequencing.
  • Deep understanding in immunology, cancer, genomics and RNA biology.
  • solid track record of performance, including successful completions of projects within a given timeframe and budget.
  • Outstanding ability to work independently and with a team- including problem solving, brainstorming, integrating data and helping other team members.
  • Excellent organizational and documentation skills.
  • Innovative approach and enthusiasm to explore new technologies.

About the AstraZeneca Site

The Waltham R&D site focuses on our small-molecule oncology research in North America, and is situated within a biopharma cluster of research institutions, medical centers, pharmaceutical companies and startups. The Boston region is consistently ranked #1 globally for research, investment, talent recruitment and lab space.

The campus, also known as the Boston BioHub, is one of the largest and most dynamic life-science research hubs in the region. It is home to more than 800 scientists working in nine different pharmaceutical and biotech companies. The site is also home to the AstraZeneca Incubator, a program that helps emerging companies advance novel and innovative healthcare solutions to meet the needs of patients. Plenty of free parking, with charging stations now available for electric vehicles, and shuttle service to local transportation hubs.

Next Steps – Apply today!

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience – it is the only way that our Recruiter and Hiring Manager can know that you feel well qualified for this opportunity. If you know someone who would be an excellent fit, please share this posting with them.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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