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Senior Scientist - Cell Therapeutics

Plats Gaithersburg, Maryland, USA Jobb-id R-101104 Datum inlagd 02/23/2021

Senior Scientist – Cell Therapeutics

Do you have expertise in, and passion for, cell therapy research? Have you published your work extensively in leading peer-reviewed journals? And would you like to apply your expertise to impact cell therapy in a company that follows the science and turns ideas into life changing medicines? Then AstraZeneca might be the place for you!


AstraZeneca is a global, innovation-driven biopharmaceutical business that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we're more than one of the world's leading pharmaceutical companies. At AstraZeneca, we're proud to have a unique workplace culture that inspires innovation and collaboration. Here, employees are empowered to express diverse perspectives - and are made to feel valued, energized and rewarded for their ideas and creativity.

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.


Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, daycare, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. 

What you’ll do

We are seeking for a Senior Scientist in the Cell Therapeutics team within the Antibody Discovery and Protein Engineering Department to support pre-clinical research of innovative therapeutic products. Expertise in T-reg biology and T-reg cell-based therapy is critical for this role. The candidate will be part of an interactive team with potential to contribute to multiple pre-clinical T-reg therapy-related technology development.  Extensive and current hands-on experience in human and mouse T-reg cell culture and assays and in vivo models is required. Work experience using viral vectors such as lentiviral vectors is desired. The ability to multi-task is critical.  A successful candidate must be well-organized and must keep an excellent written record of their work. They must also be able to communicate clearly in oral and written form with supervisor and various project team members.

Essential for the role

  • Ph.D. in Cell Biology, Immunology, or other relevant scientific discipline with 2+ years of relevant experience; or MS degree in Cell Biology or Immunology or similar field with 10+ years of relevant experience; or BS degree in Cell Biology, Immunology. Or similar field with 15+ years of relevant experience In-depth knowledge in immune cell therapy and extensive hands-on experience in CAR-T, CAR-macrophages, T-reg therapies
  • Experience with human and mouse T-reg culturing and relevant assays
  • Expertise with animal models and in vivo studies
  • Proven record of productivity as evidenced by strong publications in leading peer reviewed journals.
  • Effective communication skills and excellent team player

Desirable for the role

  • Stem cell (iPSC, ESC or HSC) differentiation into T cells
  • Viral and non-viral gene delivery systems
  • Experience in synthetic biology, chimeric receptor engineering and/or genome editing

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognising their potential. Join us on our journey of building a new kind of organisation to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what’s next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you!

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn

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AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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