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F# Research Software Engineer – Biologics Engineering, Oncology R&D

Plats Gaithersburg, Maryland, USA Jobb-id R-158967 Datum inlagd 02/10/2023

F# Research Software Engineer – Biologics Engineering, Oncology R&D

Gaithersburg, MD

The Biologics Engineering team is responsible for the discovery and optimization of next generation biological drug candidates for all key therapy areas across AstraZeneca, and for developing in-house biologics discovery platforms and novel drug modalities to address unmet medical needs.

Central to this effort is the development of end-to-end data management and analysis capabilities to deliver novel biologics drugs. You will become part of an interdisciplinary Bioinformatics team, working at the cutting edge of research and development to create an active learning system for biologics engineering, in which model predictions guide lab experiments, lab automation generates high-throughput data for model training, and predictive models are updated as new data are generated.

As part of this effort, you will work closely with experts in data management, software engineering, lab automation, computational modeling and machine learning, with access to biologics R&D data across AstraZeneca and the potential to generate new data to inform predictive models.


AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialization of prescription medicines for some of the world’s most serious diseases. But we’re more than one of the world’s leading pharmaceutical companies.

Gaithersburg, MD site

Our Gaithersburg, Maryland facility creates life-changing medicines for people around the world. This campus employs more than 3,500 experts in our field and is only a short drive from Washington, DC. This modern and vibrant scientific campus is the home of R&D and Oncology in the US. Here, we play host to some of the most cutting-edge technology and lab spaces, all designed to inspire collaboration and cross-functional science. We believe employees benefit from being challenged and inspired at work. We are dedicated to creating a culture of inclusion and collaboration.

The Gaithersburg site offers a variety of amenities to help boost productivity and help keep our employees happy and healthy. This includes a fitness center, employee healthcare clinic, electric vehicle charging stations, dry cleaning, full-service cafeteria and copy center. This is where you’ll find newly-designed, activity-based work spaces to suit a variety of working styles while increasing collaboration between teams. Come and thrive in our vibrant, energizing, connected and encouraging culture and make a difference to patients. Hear from our Senior Leaders about why they know AstraZeneca is a great place to work.


In the Oncology Business Unit we relentlessly follow the science to deliver more effective treatments to patients in need. Our dedication means we purposefully push back the limits of knowledge to change the practice of medicine. To ensure no patient is left behind, no matter what stage of disease. Fast-paced, it takes agility and responsiveness to stay committed in our pursuit of excellence. We work with focus to seek the unanswered questions – innovating, challenging accepted norms, quick decision-making and taking risks. A place of trust, it’s an opportunity to take accountability, be brave, speak up, step up and redefine Oncology, now and in the future. This is the time to join the team who is confident that cures for cancer are within our grasp.

What you’ll do

This role provides the opportunity for a talented and motivated research software engineer to develop experiment design and analysis software in F# that will significantly impact the delivery of the novel biologics drugs of the future.

  • Work collaboratively with scientists across Biologics Engineering to understand how they design laboratory experiments and analyse the resulting data. Use this knowledge to develop modular client-side web applications in F# that enable scientists to effectively design experiments and interactively analyse the results.
  • Develop software to automatically ingest data from lab automation equipment across Biologics Engineering and upload these data via web services to an end-to-end data management system based on Genedata Biologics.
  • Collaborate with machine learning experts to incorporate methods for designing novel biologics within web applications for use by scientists. Learn about leading machine learning methods for biologics design.
  • Collaborate with machine learning experts to develop an active learning system that continually trains machine learning models on data from biologics experiments and uses these data to inform subsequent experiments. Learn about leading machine learning methods for active learning applied to biologics experiments.

Essential for the Role

  • A master's degree or equivalent experience in computer science or in a relevant computational field.
  • Experience developing high-quality software in a functional programming language.
  • Experience with software development best practices.
  • A strong desire to learn about laboratory experiments for developing novel biologics therapies.
  • Experience working within a team environment.
  • Acts with integrity and does the right thing.

Desirable for the Role

  • Experience working with scientists to develop applications for research. 
  • Experience developing software in F#.
  • Experience developing F# web applications using Fable and Elmish.
  • Knowledge of molecular biology.
  • Experience developing software applications for designing molecular biology experiments or analysing the resulting data.

Why AstraZeneca?

At AstraZeneca when we see an opportunity for change, we seize it and make it happen, because any opportunity no matter how small, can be the start of something big. Delivering life-changing medicines is about being entrepreneurial - finding those moments and recognizing their potential. Join us on our journey of building a new kind of organization to reset expectations of what a bio-pharmaceutical company can be. This means we’re opening new ways to work, pioneering cutting edge methods and bringing unexpected teams together. Interested? Come and join our journey.

So, what’s next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

Where can I find out more?

Our Social Media, Follow AstraZeneca on LinkedIn

If you’re curious to know more, please contact Elva Chase, our Talent Acquisition Partner,

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We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, sex, gender, gender expression, sexual orientation, age, marital status, veteran status, or disability status. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform crucial job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorisation and employment eligibility verification requirements.

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